You combine the Binoculars (JOdHvLRy) with the Bombshot (Y8AG2010) to make the Bixplosivo Cannon (282G0010)! It would be incredibly stupid to put these up against your face, but now you have a double-barrel hand-cannon that can use virtually anything you can fit into it into explosive ammunition.
You combine the Stack of One Piece Manga (1pieceMG) with the Bunch of Bananas (5bnn!00k) to make the Ox-Ox Fruit, Model: Giraffe (1nWe0060). Eating this devil fruit allows the user to transform to and from the form of a giraffe hybrid or full giraffe at will.
American History Textbook && American Flag && Double Barreled Shotgun
You combine the American History Textbook (9um!s0T1), the American Flag (pThP2RvJ), and the Double Barreled Shotgun (3!pl?E8Z) with two consecutive ANDs to create...
The Flag Was Still There (1OW82081). This historic rifle has been lost to time, only to be returned as a legendary weapon holding the power of freedom and democracy. Any tyrant you go against is sure to fall to this thing... provided they aren't a multiple-times-prototyped end boss. Still pretty damn powerful for what looks like a normal Charlesville Musket with two barrels and a flag-bearing bayonet.